17-oh corticosteroids wikipedia

Hypophyseal portal blood concentrations of CRH are 150 times the peripheral circulating level. CRH induces the production and release of ACTH by binding to corticotrophs in the anterior pituitary via the type 1 CRH receptor which activates adenylate cyclase. 20 CRH receptors are found in the neocortex, the limbic system, the adrenal medulla, and the sympathetic ganglia. The paraventricular nucleus also is the location of many of the vasopressin-containing cells that project to the posterior pituitary. Arginine vasopressin (AVP) acts via the V1B receptor to activate protein kinase C and is highly synergistic with CRH including in ACTH release. 21 , 22  

17-oh corticosteroids wikipedia

17-oh corticosteroids wikipedia

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17-oh corticosteroids wikipedia17-oh corticosteroids wikipedia17-oh corticosteroids wikipedia17-oh corticosteroids wikipedia17-oh corticosteroids wikipedia

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