The efficacy and safety of azelastine hydrochloride nasal spray, % with sweetener in seasonal allergic rhinitis was evaluated in five randomized, multicenter, double-blind, placebo-controlled clinical trials in 2499 adult and adolescent patients 12 years and older with symptoms of seasonal allergic rhinitis (Trials 2, 3, 4, 5, and 6). The population of the trials was 12 to 83 years of age (64% female, 36% male; 81% white, 12% black, <2% Asian, 5% other; 23% Hispanic, 77% non-Hispanic). Assessment of efficacy was based on the rTNSS, iTNSS as described above, and other supportive secondary efficacy variables. The primary efficacy endpoint was the mean change from baseline in rTNSS over 2 weeks.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
1. Nasal steroid sprays aka “intranasal steroids.” Two of these are over the counter now— Flonase Allergy Relief ( fluticasone propionate ) and Nasacort Allergy ( triamcinolone acetonide )—so you can buy them and try them on your own. Intranasal steroids are more effective than oral antihistamines and should be first line treatment here. Onset of action is a few hours but they may take a few days to get rid of your cough. If it works for you, continue therapy for 3 months. For comparisons of the nasal sprays see my previous blog .