Systemic lupus erythematosus . Erythematous, edematous plaques appear in a "butterfly" distribution on the face. Lupus is an autoimmune disease characterized by acute and chronic inflammation of various tissues of the body. Common complaints and symptoms include fatigue , low-grade fever , loss of appetite , muscle aches , arthritis , ulcers of the mouth and nose, facial rash (" butterfly rash "), unusual sensitivity to sunlight (photosensitivity), inflammation of the lining that surrounds the lungs ( pleuritis ) and the heart ( pericarditis ), and poor circulation to the fingers and toes with cold exposure ( Raynaud's phenomenon ). Complications of organ involvement can lead to further symptoms that depend on the organ affected and severity of the disease. There is no permanent cure for SLE . The goal of treatment is to relieve symptoms and protect organs by decreasing inflammation and/or the level of autoimmune activity in the body.
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