A derivative of Dihydrotestosterone (DHT) and sharing a similar chemical structure of the steroid epitiostanol, once ingested, epistane binds to the receptors of the body that are responsible for building lean muscle mass. It is a readily orally active compound, meaning it is best in capsule form for oral administration over injection. Once ingested epistane works by increasing the level of activity in the cells in androgen receptors, upon binding to these receptors, epistane signals for an increased retention of nitrogen within that cell as well as an increased level of protein synthesis, leading to an increased performance as the muscles can perform/recover/grow better.
Drugs such as Nolvedex bind to the oestrogen receptors , therefore reducing the effects of the heightened oestrogen in the body. Such drugs do nothing to reduce the amount of oestrogen in the body; they merely reduce its effects via competition for the receptors . If the user wishes to reduce the amount of oestrogen they should look to drugs such as proviron and anastrozole , which are known as anti-aromatases - . they lower the conversion of the steroid to oestrogen and therefore reduces the overall amount of oestrogen present.